The origin of clean room

The origin of clean room

1.19 century in the hospital before surgery, the first to be sprayed with a stone carbonate solution, in order to control the infection, began to have the concept of clean room.

2. 1950年，高效粒子空气过滤器（HEPA）问世，成为洁净技术发展史上的第一座里程碑。

In 2.1950 years, the high efficiency particulate air filter (HEPA) has become the first milestone in the history of the development of clean technology.

3. 1963年美国颁布了洁净室第一个军用部分的联邦标准209。

In 3.1963 years the United States has issued a federal standard for the first military section of the clean room 209.

4. 1974年日本政府颁布GMP，进行指导推行。

4.1974 years, the Japanese government promulgated the GMP, to guide the implementation of.

5. 1975年世界卫生组织（WHO）正式公布GMP,1977年再次向成员国推荐GMP,并确定为WHO法规

5.1975 year WHO (WHO) officially announced the GMP, in 1977 once again to the Member States recommended GMP, and identified as WHO regulations

6. 20世纪80年代以后，美国和日本分别研制成功过滤对象为0.1μm，捕集效率达99.99%的新型

After the 6.20 century in 80s, the United States and Japan were successfully developed to filter the target for 0.1 M, the collection efficiency of 99.99% of the new

超高效过滤器。最终建成0.1μm 10级和0.1μm 1级的超高级别洁净室，它使洁净技术的发展又

Super high efficiency filter. The final completion of 0.1 M grade 10 and 0.1 grade M 1 ultra high level cleanroom, clean technology development and make it

进入一个新时期。

Enter a new era.

7. 在我国,空气洁净技术的研究始于20世纪60年代中期,GMP在我国是20世纪70年代末受到重视。

7 in our country, the study of air clean technology began in the middle of 1960s, GMP in our country is at the end of 1970s by attention.

1984年颁发了《洁净厂房设计规范》（GBJ73—84),2002年进行了修订（GB50073—2001),

In 1984 issued the "clean plant design code" (GBJ73 - 84), 2002 was revised (GB50073 - 2001),

1990年颁发了《洁净室施工及验收规范》（JGJ71—90）。

In 1990 issued the "clean room construction and acceptance norms" (JGJ71 - 90).

1998年国家药品监督管理局颁布了《药品生产质量管理规范》（GMP—98）。

In 1998, the State Drug Administration promulgated the "drug production quality management standards" (GMP - 98).